Electrospun conducting hydrogel nanomaterials for neural tissue engineering.
The aim of the proposed research project is to develop bioactive and conductive hydrogel coatings to improve the performance and biocompatibility of implantable neural electrodes. The method of healing neural system diseases and injuries with the use of electrodes appears to be a promising form of treatment. Presently, its applicability is limited by the biological tissue reaction to the electrode which causes the reduction of the implanted device operative time. The project intends to produce implant coatings capable of maintaining superb electrical properties and minimizing the inflammatory body response thanks to their biocompatibility and elasticity. The materials will be composed of polyacrylate hydrogels and polythiophene derivatives and will be produced in the form of porous nanostructured materials obtained by coaxial electrospinning. The new nanomaterials will be fabricated and characterized extensively to encourage their use in the emerging medical bionics applications.
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